JCO Oncology Practice (JCO OP) CME/CE/CPE supplement using cases to illustrate optimal interdisciplinary management of immune-related adverse events, Immuno-Oncology Essentials: Applications in Clinical Scenarios.

Immuno-Oncology Essentials: Applications in Clinical Scenarios—Introduction

In this introductory section, editor Yiyi Yan, MD, PhD, reviews the common themes across the 4 supplement articles.

Toxicity Management of Front-Line Pembrolizumab Combined With Axitinib in Clear Cell Metastatic Renal Cell Carcinoma: A Case Study Approach

In this article, Laura S. Wood, RN, MSN, OCN, and Moshe C. Ornstein, MD, MA, demonstrate the evaluation and management of side effects occurring with the combination of immune checkpoint and kinase inhibitor therapy in a patient with renal cell carcinoma.

Management of Pneumonitis and Neuropathy in Patients Receiving PD-1–Based Therapy for Non–Small-Cell Lung Cancer

In this article, Marianne J. Davies, DNP, MSN, RN, APRN, CNS-BC, ACNP-BC, AOCNP, and Anne C. Chiang, MD, PhD, discuss the recognition and management of the rare immune-related adverse events of pneumonitis and neuropathy in a patient with NSCLC.

Management of Immune-Related Dermatitis and Mucositis Associated With Pembrolizumab in Metastatic Human Papillomavirus–Associated Squamous Cell Carcinoma of the Oropharynx

This article, authored by Casey Fazer, PA-C, and Katharine A. Price, MD, reviews the management of both dermatitis and mucositis in a patient receiving checkpoint inhibitor therapy for HNSCC, illustrating the importance of early assessment and management.

Atypical Presentations and Management of Endocrine and Hepatic Immune-Related Adverse Events From Adjuvant Immune Checkpoint Inhibitor Therapy in Stage III Resected Melanoma

In this article, Lisa A. Kottschade, APRN, MSN, CNP, and Yiyi Yan, MD, PhD, illustrate the evaluation and management of endocrinopathy and liver toxicity in a patient with melanoma receiving immune checkpoint inhibitor therapy, addressing overlapping toxicities and strategies to tease out the root cause of endocrine dysfunction.